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less sensitive sense of smell is the first sign of Alzheimer's disease

less sensitive sense of smell is the first sign of Alzheimer's diseaseAs shown by scientists in the development of Alzheimer's disease, primarily the perception of odors as a result of the death of olfactory cells and neurons, responsible for the sense of smell. As Richard says Doty (Director of the center for diseases of taste and smell of Pennsylvania medical center, Philadelphia, USA): "most of the patients as Alzheimer's and Parkinson's disease, already in the early stages of the disease there is a loss of smell. This symptom may serve as targets for early diagnosis and destination effective treatment". Dr. Doty and his colleagues showed that the cause of death of olfactory cells is the formation of a large number of so-called protein "Tau" in areas of the brain responsible for smell. To study the effect of Tau on the sense of smell, scientists have created a special, genetically modified breed of mice, brain cells are produced pathogenic protein in large quantities. In these mice quickly developed Alzheimer's disease. Scientists have shown that mice that produce "Tau" there are very bad smells, and the development of Alzheimer's smell, they do not. Thus, the loss of smell is a dangerous and important in old age symptom, talking about the risk of developing Alzheimer's disease..

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